How does this medicine work?

Vincristine (vin-kris-teen) destroys cancer cells by interfering with a specific phase of cell life. It is also used to increase the platelets in the blood by blocking the activity of macrophages, blood cells that normally destroy platelets.

How is the medicine given?

Vincristine is given by rapid push into the vein (IV) in the hospital or clinic.

What are the side effects?


  • hair loss
  • tingling in hands and feet
  • muscle weakness
  • jaw pain
  • constipation


  • low-blood counts
  • seizures
  • low-grade fever

When should I call the clinic?

Call hematology helpline 982403210 if:

  • fever higher than 100.4º F
  • chills
  • bleeding
  • unusual bruising
  • tingling or weakness of hands or feet
  • jaw pain that paracetamol does not help
  • no bowel movement for 2 days or more
  • seizures

What else do I need to know?

A high-fiber diet or stool softener may be given to prevent or treat constipation.

Tissue burns may occur if the medicine leaks from a vein.

Most neurologic effects (such as jaw pain, tingling, and muscle weakness) are reversible after stopping or decreasing the dosage of the medicine.

You and your child should know the names of all the medicines he or she is taking. It is important to share this information with anyone involved in your child’s care.


This sheet is not specific to your child but provides general information. If you have any questions, please call:

Hematology Clinic
3rd floor, Kedar
Opp.Krupa Petrol Pump,
Parimal Garden, Ambawadi
Clinic: 07926463219
Whattsapp: 8238065890