How does this medicine work?
Temozolomide (te-moh-zol-oh-mide) destroys cancer cells in all phases of cell life.
How is it given?
Temozolomide is given by mouth. It comes in capsule form and should be swallowed whole. It should be given at regular times to keep a steady level in the bloodstream.
For children who cannot swallow capsules:
- Put on gloves.
- Open capsule inside a clear plastic bag.
- Mix the powder with a very small amount (1 teaspoon) of soft food, such as applesauce or applejuice. Make sure your child takes all of the mixture.
- Wash spoons and container right after use. Discard the plastic bag and gloves.
Are there any precautions about food or other medications?
Temozolomide should be taken on an empty stomach with water only, to reduce nausea and to help the body to absorb and use the medicine. It needs to be taken at a consistent time each day with regard to meals.
Check with the doctor, nurse practitioner, or pharmacist before giving any other prescription or non-prescription medicines, herbs, or vitamins.
What should I do if a dose is missed?
If a dose is missed, give it as soon as you remember that day. Never give a double dose.
If your child vomits within 30 minutes after receiving a dose, give it again. If your child vomits after 30 minutes, do not repeat the dose.
Call the oncology clinic if more than one dose is missed or vomited.
What are the side effects?
- low blood counts
- hair loss
- mouth sores
- liver problems
- skin rash
- coordination problems