How does this medicine work?
Irinotecan destroys cancer cells by interfering with a specific phase of cell life.
How is it given?
Irinotecan is given by intravenous (into the vein) infusion.
What are the side effects?
Common
- low blood cell counts
- sweating
- increased saliva
- severe diarrhea (see diarrhea management on the back of this page)
- nausea
- vomiting
- loss of appetite
- belly pain/cramping
- hair loss
Occasional
- mouth sores
- fatigue (tired)
- pain at injection site
Rare
- change in liver function
- change in kidney function
- rash
- itching of the skin
- redness and warmth in the face
When should I call the clinic?
Call the hematology helpline 982403210 if:
- fever
- chills
- diarrhea (more than 4 stools a day)
- mouth sores
What else do I need to know?
Blood counts are lowest 10 to 21 days after the medicine is given.
It is important to follow the instructions for managing diarrhea with the medicine Imodium® on the back of this page.
You and your child should know the names of all the medicines he or she is taking. It is important to share this information with anyone involved in your child’s care.
What are the side effects?
Common
- low blood cell counts
- bleeding, anemia
- nausea, vomiting
- heartburn
Occasional
- headache
- stomach pain, cramping
- muscle aches
- edema (swelling)
- rash
- fever
- tiredness
- change in liver function