How does this medicine work?

Ifosfamide (eye-foss-fuh-mide) destroys cancer cells in all phases of cell life.

How is it given?

It is given into the vein (IV) in the hospital or clinic.

What are the side effects?


  • low blood cell counts
  • nausea, vomiting
  • hair loss
  • feeling tired
  • loss of appetite


  • abnormal liver function
  • bladder irritation


  • kidney damage
  • confusion
  • sleepiness
  • seizures

When should I call the clinic?

Call hematology helpline 982403210 if:

  • fever
  • sore throat
  • cough
  • bleeding, bruising
  • mouth sores
  • continued vomiting
  • pain in the stomach, joints, or side
  • pain or blood with urination
  • seizures
  • shortness of breath

What else do I need to know?

All caregivers should wear gloves when handling urine, stool, and vomit while your child is receiving the chemotherapy and for 48 hours afterward. Urine, stool, and vomit can be safely disposed of in septic tanks and the sewer system.

Blood counts are lowest in 1 to 2 weeks after the medicine is given.

Important: Ifosfamide is removed from the body through the kidneys. A high fluid intake will help prevent bladder irritation.
Encourage your child to drink twice the normal amount of fluids for 24 hours after ifosfamide is given.

Encourage your child to urinate often.

Medicines may be given to help reduce nausea and vomiting.

To prevent bladder irritation, a medicine called mesna is given to protect the bladder, and IV fluids are given to flush the ifosfamide out of the bladder.

You and your child should know the names of all the medicines he or she is taking. It is important to share this information with anyone involved in your child’s care.

Check with the doctor before giving any other prescription or non-prescription medicines, herbs, or vitamins.


This sheet is not specific to your child but provides general information. If you have any questions, please call:

Hematology Clinic
3rd floor, Kedar
Opp.Krupa Petrol Pump,
Parimal Garden, Ambawadi
Clinic: 07926463219