How does this medicine work?
Hydroxyurea (hye-drok-see-yur-ee-uh) destroys cancer cells by interfering with a specific phase of the cell life cycle. It is also used to help produce normal hemoglobin in persons with sickle cell disease.
How should I give it?
Hydroxyurea comes in capsule form. Give it at regular times to keep a steady level in the bloodstream. Your child should be awake and alert when taking any medicine.
If your child cannot swallow it, put on gloves, open it inside a clear plastic bag, mix the contents with water, and have your child drink it right away. Then wash the glass immediately, and discard the plastic bag and gloves.
Are there any precautions about food or other medicines?
This medicine should be given on an empty stomach (one hour before or two hours after eating). Taking it after meals or at bedtime may reduce the loss of appetite due to the medicine.
Check with the doctor, before giving any other prescription or non-prescription medicines, herbs, or vitamins.
Drink plenty of fluids while taking this medicine.
What should I do if a dose is missed?
If a dose is missed, give it as soon as you remember that day. Never give a double dose.
If your child throws up within 30 minutes after receiving a dose, give it again. If your child vomits after 30 minutes, do not repeat the dose. Call the oncology clinic if more than one dose is missed or vomited.
What are the side effects?
Occasional
- low blood cell counts
- loss of appetite
- skin rash
- mouth sores
- hair loss
- drowsiness
- mild nausea
- vomiting
Rare
- headaches
- liver or kidney damage
- hallucinations
- disorientation
- lung disease