How does this medicine work?
Fludarabine (flew-dare-a-bean) interferes with the cells’ ability to make DNA. This prevents cancer cells from multiplying.
How is it given?
Fludarabine is given by infusion into the vein (IV) in the hospital or clinic.
Are there any precautions about food or other medicines?
Check with the doctor, nurse practitioner, or pharmacist before giving any other prescription or non-prescription medicines, vaccines, vitamins, or herbs.
What are the side effects?
Common
- low blood cell counts
- nausea, vomiting
- changes blood electrolytes
- fever
Occasional
- chills
- extreme tiredness
- diarrhea
- mouth sores
- nerve tissue damage
- numbness
- blurred vision
- eye sensitivity to bright light
- joint pain
- weakness
- seizures
- immune supressed
- increased salts in the blood due to tumor cell destruction
Rare
- rash
- liver injury
- kidney injury
- lung damage, including shortness of breath, coughing, and pneumonia
- worsening of nervous system problems, which can lead to:
- blindness
- paralysis
- confusion and coma
- muscle weakness
- thinning of nerve fibers, which can lead to:
- loss of memory and concentration
- loss of balance and ability to walk