How does this medicine work?

Asparaginase (as-par-a-gin-ace) destroys leukemia cancer cells in all phases of cell life.

How should I give it?

It is given by injection (shot) into the muscle in the hospital or clinic.

What are the side effects?


  • change in blood clotting factors


  • mild nausea
  • vomiting
  • high blood sugar
  • headache
  • fatigue
  • loss of appetite
  • signs of allergic reaction:
    •  fever or chills
    •  rash or hives
    •  wheezing
    • trouble breathing
    •  redness at injection site


  • changes in liver or kidney function
  • loss of appetite
  • pancreatitis
  • blood clotting problems

When should I call the clinic?

Call hematology helpline 982403210 if:

    • fever, chills
    • unusual bleeding or bruising
    • unable to move arms or legs
    • joint or stomach pain
    • skin rash or itching
    • pain with urination or urinating more than normal
    • extremely thirsty
    • trouble breathing – call 112

    What else do I need to know?

    The urine will need to be checked at times for glucose (sugar).

    Due to the chance of allergic reactions, patients should stay in the clinic for observation for 30 to 60 minutes after the medicine is given.

    You and your child should know the names of all the medicines he or she is taking. It is important to share this information with anyone involved in your child’s care.


    This sheet is not specific to your child but provides general information. If you have any questions, please call:

    Hematology Clinic
    3rd floor, Kedar
    Opp.Krupa Petrol Pump,
    Parimal Garden, Ambawadi
    Clinic: 07926463219
    Whattsapp: 8238065890